Gary Perdew

• Distinguished Professor of Veterinary Science
• Director of the Center for Molecular Toxicology and Carcinogenesis
• John T. and Paige S. Smith Professorship in Agricultural Sciences
• 309 Life Sciences Building
• University Park
• Telephone: (814) 865-0400
• FAX: (814) 863-6140
• E-mail: ghp2@psu.edu
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• Department faculty webpage
• The Perdew Research Group
• Center for Molecular Toxicology and Carcinogenesis

Keywords:

• Biochemistry
• Cancer or Carcinogenesis
• Cell Biology/Physiology
• Gene Expression
• Genomics
• Health and the Environment
• Ligands
• Molecular Biology
• Molecular Dynamics
• Nuclear Receptors
• Proteins and Macromolecules
• Signal Transduction
• Toxicogenomics
• Toxicology
• Transcription

Active Research Projects:

• Activation of the Ah Receptor by Tetranor 12-HETE
• Biochemical Characterization of PPAR (Year 11)
• Regulation of TCDD-Mediated Gene Expression and Liver Toxicity by the Human vs. Mouse Ah Receptor

Completed Research Projects:

• Biochemical Analysis of the Human versus Mouse Ah Receptor IV
• Biochemical analysis of the human vs. mouse Ah receptor I
• Biochemical analysis of the human vs. mouse Ah receptor II
• Biochemical Analysis of the Human vs. Mouse Ah Receptor III
• Biochemical Characterization of PPAR - Year 9
• Biochemical Characterization of PPAR (Year 10)
• Biochemical Characterization of PPAR VII
• Cloning of Ah Receptor Bound Regulatory DNA - Year II
• Cloning of Ah receptor bound regulatory DNA-Year 1
• Endogenous CYP1B1 Substrates as AhR Ligands
• Protein Kinase Mediated Regulation of the AH Receptor